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Article

The diversification of the LIM superclass at the base of the metazoa increased subcellular complexity and promoted multicellular specialization.

PloS one - 1 Jan 2012

Koch Bernard J, Ryan Joseph F, Baxevanis Andreas D

Abstract excerpt

BACKGROUND: Throughout evolution, the LIM domain has been deployed in many different domain configurations, which has led to the formation of a large and distinct group of proteins. LIM proteins are involved in relaying stimuli received at the cell surface to the nucleus in order to regulate cell structure, motility, and division. Despite their fundamental roles in cellular processes and human disease, little is...

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Identifiers

PMID: 22438907
DOI: 10.1371/journal.pone.0033261
PMCID: PMC3305314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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