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Article

Mutant p53 protects ETS2 from non-canonical COP1/DET1 dependent degradation.

Oncotarget - 15 Mar 2016

Carrero Zunamys I, Kollareddy Madhusudhan, Chauhan Krishna M, Ramakrishnan Gopalakrishnan, Martinez Luis A

Abstract excerpt

Mutations in the tumor suppressor gene TP53 contribute to the development of approximately half of all human cancers. One mechanism by which mutant p53 (mtp53) acts is through interaction with other transcription factors, which can either enhance or repress the transcription of their target genes. Mtp53 preferentially interacts with the erythroblastosis virus E26 oncogene homologue 2 (ETS2), an ETS transcription...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26871468
DOI: 10.18632/oncotarget.7275
PMCID: PMC4914304

Genes

ETS2
DET1
COP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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