Article
Altered profile of regulatory T cells and associated cytokines in mild and moderate dengue.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Mar 2016
Tillu H, Tripathy A S, Reshmi P V, Cecilia D
Abstract excerpt
The pathogenesis of dengue is immune-mediated. Regulatory T cells suppress immune response and may contribute to better prognosis. The present study evaluates Tregs and cytokines in dengue patients in the context of disease severity, time of sampling and immune status. The cohort included 90 patients (51 mild, 39 moderate) and 27 healthy controls. Frequencies of Tregs, CD4(+)CD25(-)Foxp3(+) T cells and CD3(+),...
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