Article
Regulatory T-cells in acute dengue viral infection.
Immunology - 1 May 2018
Jayaratne Hemadri Eresha, Wijeratne Dulharie, Fernando Samitha, Kamaladasa Achala, Gomes Laksiri, Wijewickrama Ananda, Ogg Graham Stuart, Malavige Gathsaurie Neelika
Abstract excerpt
Although regulatory T-cells (Tregs ) have been shown to be expanded in acute dengue, their role in pathogenesis and their relationship to clinical disease severity and extent of viraemia have not been fully evaluated. The frequency of Tregs was assessed in 56 adult patients with acute dengue by determining the proportion of forkhead box protein 3 (FoxP3) expressing CD4+ CD25+ T-cells (FoxP3+ cells). Dengue virus...
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