Article
Interleukin-1β gene variants are associated with QTc interval prolongation following cardiac surgery: a prospective observational study.
Canadian journal of anaesthesia = Journal canadien d'anesthesie - 1 Apr 2016
Kertai Miklos D, Ji Yunqi, Li Yi-Ju, Mathew Joseph P, Daubert James P, Podgoreanu Mihai V
Abstract excerpt
BACKGROUND: We characterized cardiac surgery-induced dynamic changes of the corrected QT (QTc) interval and tested the hypothesis that genetic factors are associated with perioperative QTc prolongation independent of clinical and procedural factors. METHODS: All study subjects were ascertained from a prospective study of patients who underwent elective cardiac surgery during August 1999 to April 2002. We defined...
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