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Article

Genome-wide association study in mice identifies loci affecting liver-related phenotypes including Sel1l influencing serum bile acids.

Hepatology (Baltimore, Md.) - 1 Jun 2016

Wu Wei, Patel Ami, Kyöstilä Kaisa, Lohi Hannes, Mladkova Nikol, Kiryluk Krzysztof, Sun Xiaoyun, Lefkowitch Jay H, Worman Howard J, Gharavi Ali G

Abstract excerpt

UNLABELLED: Using publicly available data from inbred mouse strains, we conducted a genome-wide association study to identify loci that accounted for liver-related phenotypes between C57BL/6J and A/J mice fed a Paigen diet. We confirmed genome-wide significant associations for hepatic cholesterol (chromosome 10A2) and serum total bile acid concentration (chromosome 12E) and identified a new locus for liver...

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PMID: 26857093
DOI: 10.1002/hep.28495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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