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Article

Hepatocyte nuclear factor-4α promotes differentiation of intestinal epithelial cells in a coculture system

22 Nov 2007

Abstract excerpt

Normal cellular models able to efficiently recapitulate intestinal epithelial cell differentiation in culture are not yet available. The aim of this work was to establish and genetically characterize a mesenchymal-epithelial coculture system to identify transcriptional regulators involved in this process. The deposition of rat intestinal epithelial cells on human intestinal mesenchymal cells led to the formation...

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PMID: 18032476
DOI: 10.1152/ajpgi.00418.2007

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