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Article

Genetic variants associated with triglyceride metabolism and fasting triglyceride concentrations: a systematic review and a meta-analysis.

Journal of clinical lipidology - 1 Aug 2026

Nuwaylati Dena A, Mensink Ronald P, Joris Peter J, Coort Susan L M, Plat Jogchum

Abstract excerpt

BACKGROUND AND OBJECTIVE: The genetic background of hypertriglyceridemia is complex. In this systematic review and meta-analysis, we determined genetic variants associated with fasting triglyceride (TG) and very-low-density lipoprotein-TG (VLDL-TG) concentrations in European adults. METHODS: We searched PubMed and the National Human Genome Research Institute-European Bioinformatics Institute (NHGRI-EBI)...

Topics

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Apolipoprotein A-V
Apolipoprotein C-III
Fasting
Genetic Variation
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipoprotein Lipase

Lipoproteins, VLDL

Source

Identifiers

PMID: 42448503
DOI: 10.1016/j.jacl.2026.06.019

Genes

TG
APOA5
APOB
APOC3
LIPC
LPL
PNPLA3
PON1
TCF7L2
TM6SF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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