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Article

Characterizing the Molecular Pathology of Arrhythmogenic Cardiomyopathy in Patient Buccal Mucosa Cells.

Circulation. Arrhythmia and electrophysiology - 1 Feb 2016

Asimaki Angeliki, Protonotarios Alexandros, James Cynthia A, Chelko Stephen P, Tichnell Crystal, Murray Brittney, Tsatsopoulou Adalena, Anastasakis Aris, te Riele Anneline, Kléber André G, Judge Daniel P, Calkins Hugh, Saffitz Jeffrey E

Abstract excerpt

BACKGROUND: Analysis of myocardium has revealed mechanistic insights into arrhythmogenic cardiomyopathy but cardiac samples are difficult to obtain from probands and especially from family members. To identify a potential surrogate tissue, we characterized buccal mucosa cells. METHODS AND RESULTS: Buccal cells from patients, mutation carriers, and controls were immunostained and analyzed in a blinded fashion. In...

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Identifiers

PMID: 26850880
DOI: 10.1161/CIRCEP.115.003688
PMCID: PMC4785796

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PKP2
DSC2
DSG2
DSP
JUP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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