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Article

Selenoprotein gene variants, toenail selenium levels, and risk for advanced prostate cancer.

Journal of the National Cancer Institute - 1 Mar 2014

Geybels Milan S, van den Brandt Piet A, Schouten Leo J, van Schooten Frederik J, van Breda Simone G, Rayman Margaret P, Green Fiona R, Verhage Bas A J

Abstract excerpt

Lower selenium levels have been associated with increased risk of prostate cancer (PCa), and genetic variation in the selenoprotein genes selenoprotein P (SEPP1) and glutathione peroxidase 1 (GPX1) is thought to modify this relationship. We investigated whether the association between toenail selenium levels and advanced PCa risk in the prospective Netherlands Cohort Study is modified by common genetic variation...

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Identifiers

PMID: 24563517
DOI: 10.1093/jnci/dju003

Genes

GPX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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