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Article

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.

Scientific reports - 5 Feb 2016

Li Sam X, Barrett Bradley S, Guo Kejun, Kassiotis George, Hasenkrug Kim J, Dittmer Ulf, Gibbert Kathrin, Santiago Mario L

Abstract excerpt

Tetherin/BST-2 is a host restriction factor that inhibits retrovirus release from infected cells in vitro by tethering nascent virions to the plasma membrane. However, contradictory data exists on whether Tetherin inhibits acute retrovirus infection in vivo. Previously, we reported that Tetherin-mediated inhibition of Friend retrovirus (FV) replication at 2 weeks post-infection correlated with stronger natural...

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Identifiers

PMID: 26846717
DOI: 10.1038/srep20425
PMCID: PMC4742778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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