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Article

The Link Between CD6 and Autoimmunity: Genetic and Cellular Associations.

Current drug targets - 1 Jan 2016

Kofler David M, Farkas Aron, von Bergwelt-Baildon Michael, Hafler David A

Abstract excerpt

The cell surface glycoprotein CD6 is expressed on leukocytes and mediates T cell trafficking across endothelial cell barriers. There is evidence suggesting that CD6 is implicated in the pathogenesis of autoimmune diseases, including multiple sclerosis (MS) and rheumatoid arthritis (RA). CD166, the physiological ligand of CD6, is expressed on endothelial cells in the central nervous system and in the collagen...

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Share to Antigens, Differentiation, T-Lymphocyte
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to CD4-Positive T-Lymphocytes

Share to Cell Adhesion Molecules, Neuronal

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Source

Identifiers

PMID: 26844569
DOI: 10.2174/1389450117666160201105934

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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