Article
Annotation of functional variation within non-MHC MS susceptibility loci through bioinformatics analysis.
Genes and immunity - 1 Oct 2014
Briggs F B S, Leung L J, Barcellos L F
Abstract excerpt
There is a strong and complex genetic component to multiple sclerosis (MS). In addition to variation in the major histocompatibility complex (MHC) region on chromosome 6p21.3, 110 non-MHC susceptibility variants have been identified in Northern Europeans, thus far. The majority of the MS-associated genes are immune related; however, similar to most other complex genetic diseases, the causal variants and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
