Article
[Dynamic changes of basal core promoter and pre-core mutants of hepatitis B virus in patients with chronic hepatitis B virus infection].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Mar 1999
Chen J, Hou J, Wang Z
Abstract excerpt
OBJECTIVES: To clarify the association of hepatitis B virus mutants in basal core gene promoter and pre-c region with serum HBeAg state and persistent HBV infection. METHODS: 32 patients, who infected with hepatitis B virus and suffered from several exacerbation during the course of this disease, were followed up for an average of 20.8 months. Using two mis-matched primers to amplify BCP and pre-c gene fragments,...
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