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A subcelluar proteomic investigation into vincristine‐resistant gastric cancer cell line

5 Feb 2008

Abstract excerpt

Multidrug resistance (MDR) is a major obstacle to successful cancer treatment. To understand the mechanism of MDR better, a subcelluar proteomics approach was used to compare the protein profile between vincristine-resistant human gastric cancer cell line SGC7901/VCR and its parental cell line SGC7901. After differential solubilization, the subfractionation proteins were separate by two-dimensional gel...

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PMID: 18253933
DOI: 10.1002/jcb.21687

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