Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Evolution during the development of an attenuated EIAV vaccine.

Retrovirology - 3 Feb 2016

Wang Xue-Feng, Lin Yue-Zhi, Li Qiang, Liu Qiang, Zhao Wei-Wei, Du Cheng, Chen Jie, Wang Xiaojun, Zhou Jian-Hua

Abstract excerpt

BACKGROUND: The equine infectious anemia virus (EIAV) vaccine is the only attenuated lentiviral vaccine applied on a large scale that has been shown to be effective in controlling the prevalence of EIA in China. This vaccine was developed by successive passaging of a field-isolated virulent strain in different hosts and cultivated cells. To explore the molecular basis for the phenotype alteration of this vaccine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Equidae
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Horses

Share to Infectious Anemia Virus, Equine

Share to Serial Passage

Share to Vaccines, Attenuated

Share to Viral Vaccines

Source

Open in PubMed Open full text

Identifiers

PMID: 26842878
DOI: 10.1186/s12977-016-0240-6
PMCID: PMC4738788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Evolution during the development of an attenuated EIAV vaccine.PMID 26842878Read ↗

Genomic analysis of an effective lentiviral vaccine-attenuated equine infectious anemia virus vaccine EIAV FDDV13.Semantic proximity Read ↗

Genomic comparison between attenuated Chinese equine infectious anemia virus vaccine strains and their parental virulent strains.Semantic proximity Read ↗

EIAV envelope diversity: shaping viral persistence and encumbering vaccine efficacy.Semantic proximity Read ↗

Amino acid mutations of the infectious clone from Chinese EIAV attenuated vaccine resulted in reversion of virulence.Semantic proximity Read ↗

Env diversity-dependent protection of the attenuated equine infectious anaemia virus vaccine.Semantic proximity Read ↗

Genetic variation in the long terminal repeat associated with the transition of Chinese equine infectious anemia virus from virulence to avirulence.Semantic proximity Read ↗

Rational design of a live-attenuated eastern equine encephalitis virus vaccine through informed mutation of virulence determinantsSemantic proximity Read ↗

Genetic evolution of equine influenza viruses isolated in ChinaSemantic proximity Read ↗

In vivo evolution of the gp90 gene and consistently low plasma viral load during transient immune suppression demonstrate the safety of an attenuated equine infectious anemia virus (EIAV) vaccine.Semantic proximity Read ↗

Genetic evolution of equine influenza virus strains (H3N8) isolated in France from 1967 to 2015 and the implications of several potential pathogenic factorsSemantic proximity Read ↗

Viral Live‐Attenuated Vaccines (LAVs): Past and Future DirectionsSemantic proximity Read ↗

A pilot study on interaction between donkey tetherin and EIAV stains with different virulent and replication characteristics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.