Article
Genomic analysis of an effective lentiviral vaccine-attenuated equine infectious anemia virus vaccine EIAV FDDV13.
Virus genes - 1 Aug 2010
Qi Xu, Wang Xuefeng, Wang Shuai, Lin Yuezhi, Jiang Chenggang, Ma Jian, Zhao Liping, Lv Xiaoling, Shen Rongxian, Wang Fenglong, Kong Xiangang, Su Zhiqiang, Zhou Jianhua
Abstract excerpt
Chinese equine infectious anemia virus (EIAV) attenuated vaccine is the first lentiviral vaccine with a successful application. In order to understand the correlation of viral genomic mutations with viral attenuation and with induced immunoprotective properties, we analyzed the proviral genome sequences of the EIAV-attenuated vaccine strain EIAV(FDDV13) (EIAV fetal donkey dermal cell-adapted vaccine) and its...
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