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Article

Genetic variation in the long terminal repeat associated with the transition of Chinese equine infectious anemia virus from virulence to avirulence.

Virus genes - 1 Apr 2009

Wei Lili, Fan Xiujuan, Lu Xiaoling, Zhao Liping, Xiang Wenhua, Zhang Xiaoyan, Xue Fei, Shao Yiming, Shen Rongxian, Wang Xiaojun

Abstract excerpt

A highly virulent strain of equine infectious anemia virus (EIAV) lost its fatal virulence but retained the desired antigens during serial passage over 130 generations in leukocytes in vitro. We compared the long terminal repeat (LTR) sequences of the different generations and found that three stable genetic variations occurred in the transcriptional start site, the initial base of TAR, and the pre-mRNA cleavage...

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Source

Identifiers

PMID: 19130201
DOI: 10.1007/s11262-008-0317-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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