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Article

CCL2 Serum Levels and Adiposity Are Associated with the Polymorphic Phenotypes -2518A on CCL2 and 64ILE on CCR2 in a Mexican Population with Insulin Resistance.

Journal of diabetes research - 1 Jan 2016

Guzmán-Ornelas Milton-Omar, Petri Marcelo Heron, Vázquez-Del Mercado Mónica, Chavarría-Ávila Efraín, Corona-Meraz Fernanda-Isadora, Ruíz-Quezada Sandra-Luz, Madrigal-Ruíz Perla-Monserrat, Castro-Albarrán Jorge, Sandoval-García Flavio, Navarro-Hernández Rosa-Elena

Abstract excerpt

Genetic susceptibility has been described in insulin resistance (IR). Chemokine (C-C motif) ligand-2 (CCL2) is overexpressed in white adipose tissue and is the ligand of C-C motif receptor-2 (CCR2). The CCL2 G-2518A polymorphism is known to regulate gene expression, whereas the physiological effects of the CCR2Val64Ile polymorphism are unknown. The aim of the study is to investigate the relationship between these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26839895
DOI: 10.1155/2016/5675739
PMCID: PMC4709622

Genes

CCL2
CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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