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Article

The Impact of LEP G-2548A and LEPR Gln223Arg Polymorphisms on Adiposity, Leptin, and Leptin-Receptor Serum Levels in a Mexican Mestizo Population.

BioMed research international - 1 Jan 2015

Chavarria-Avila Efraín, Vázquez-Del Mercado Mónica, Gomez-Bañuelos Eduardo, Ruiz-Quezada Sandra-Luz, Castro-Albarran Jorge, Sánchez-López Lizeth, Martín-Marquez Beatriz Teresita, Navarro-Hernández Rosa-Elena

Abstract excerpt

The polymorphisms in leptin (LEP G-2548A) and leptin-receptor (LEPR Gln223Arg) seem to influence obesity and lipid metabolism among others. The aim of this study was to investigate the effect of these polymorphisms on adiposity, leptin (sLeptin), and leptin-receptor (sLeptin-receptor) serum concentrations as well as inflammation markers. We included 382 adults originally from Western Mexico. They were genotyped...

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Share to Adiposity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26064921
DOI: 10.1155/2015/539408
PMCID: PMC4441989

Genes

LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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