Article
The 482Ser of PPARGC1A and 12Pro of PPARG2 Alleles Are Associated with Reduction of Metabolic Risk Factors Even Obesity in a Mexican-Mestizo Population.
BioMed research international - 1 Jan 2015
Vázquez-Del Mercado Mónica, Guzmán-Ornelas Milton-Omar, Corona Meraz Fernanda-Isadora, Ríos-Ibarra Clara-Patricia, Reyes-Serratos Eduardo-Alejandro, Castro-Albarran Jorge, Ruíz-Quezada Sandra-Luz, Navarro-Hernández Rosa-Elena
Abstract excerpt
The aim of this study was to investigate the relationship between functional polymorphisms Gly482Ser in PPARGC1A and Pro12Ala in PPARG2 with the presence of obesity and metabolic risk factors. We included 375 individuals characterized as Mexican-Mestizos and classified by the body mass index (BMI). Body dimensions and distribution of body fat were measured. The HOMA-IR and adiposity indexes were calculated....
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