Article
The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypes.
Scientific reports - 7 Apr 2017
Djenoune Lydia, Desban Laura, Gomez Johanna, Sternberg Jenna R, Prendergast Andrew, Langui Dominique, Quan Feng B, Marnas Hugo, Auer Thomas O, Rio Jean-Paul, Del Bene Filippo, Bardet Pierre-Luc, Wyart Claire
Abstract excerpt
Chemical and mechanical cues from the cerebrospinal fluid (CSF) can affect the development and function of the central nervous system (CNS). How such cues are detected and relayed to the CNS remains elusive. Cerebrospinal fluid-contacting neurons (CSF-cNs) situated at the interface between the CSF and the CNS are ideally located to convey such information to local networks. In the spinal cord, these GABAergic...
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