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Article

Association between glioma susceptibility loci and tumour pathology defines specific molecular etiologies.

Neuro-oncology - 1 May 2013

Di Stefano Anna Luisa, Enciso-Mora Victor, Marie Yannick, Desestret Virginie, Labussière Marianne, Boisselier Blandine, Mokhtari Karima, Idbaih Ahmed, Hoang-Xuan Khe, Delattre Jean-Yves, Houlston Richard S, Sanson Marc

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified single-nucleotide polymorphisms (SNPs) at 7 loci influencing glioma risk: rs2736100 (TERT), rs11979158 and rs2252586 (EGFR), rs4295627 (CCDC26), rs4977756 (CDKN2A/CDKN2B), (PHLDB1), and (RTEL1). MATERIALS AND METHODS: We studied the relationship among these 7 glioma-risk SNPs and characteristics of tumors from 1374 patients, including...

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Source

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Identifiers

PMID: 23161787
DOI: 10.1093/neuonc/nos284
PMCID: PMC3635509

Genes

EGFR
PHLDB1
RTEL1
TERT
IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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