Article
Colorectal cancer-derived microvesicles modulate differentiation of human monocytes to macrophages.
Journal of translational medicine - 2 Feb 2016
Baj-Krzyworzeka Monika, Mytar Bożenna, Szatanek Rafał, Surmiak Marcin, Węglarczyk Kazimierz, Baran Jarek, Siedlar Maciej
Abstract excerpt
BACKGROUND: Tumour-derived microvesicles (TMVs) are important players in tumour progression, modulating biological activity of immune cells e.g. lymphocytes, monocytes and macrophages. This phenomenon is particularly interesting in the progression of colon cancer, as macrophages in this type of tumour are relevant for the recovery processes. In the present study, the role of colon cancer cell-derived...
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