Article
Age-related change in γH2AX of Drosophila muscle: its significance as a marker for muscle damage and longevity.
Biogerontology - 1 Aug 2015
Jeon Ho-Jun, Kim Young-Shin, Park Joung-Sun, Pyo Jung-Hoon, Na Hyun-Jin, Kim In-Joo, Kim Cheol-Min, Chung Hae Young, Kim Nam Deuk, Arking Robert, Yoo Mi-Ae
Abstract excerpt
Muscle aging is closely related to unhealthy late-life and organismal aging. Recently, the state of differentiated cells was shown to be critical to tissue homeostasis. Thus, understanding how fully differentiated muscle cells age is required for ensuring healthy aging. Adult Drosophila muscle is a useful model for exploring the aging process of fully differentiated cells. In this study, we investigated...
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