Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipid droplets control the maternal histone supply of Drosophila embryos.

Current biology : CB - 20 Nov 2012

Li Zhihuan, Thiel Katharina, Thul Peter J, Beller Mathias, Kühnlein Ronald P, Welte Michael A

Abstract excerpt

BACKGROUND: Histones are essential for chromatin packing, yet free histones not incorporated into chromatin are toxic. While in most cells multiple regulatory mechanisms prevent accumulation of excess histones, early Drosophila embryos contain massive extranuclear histone stores, thought to be essential for development. Excess histones H2A, H2B, and H2Av are bound to lipid droplets, ubiquitous fat storage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Drosophila Proteins
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histones

Share to Lipid Metabolism

Share to Lipids

Share to Multiprotein Complexes

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 23084995
DOI: 10.1016/j.cub.2012.09.018
PMCID: PMC3513403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipid droplets control the maternal histone supply of Drosophila embryos.PMID 23084995Read ↗

Histones: sequestered by Jabba in fatty storehouse.Semantic proximity Read ↗

Histone variants in development and diseases.Semantic proximity Read ↗

H2AK119ub1 guides maternal inheritance and zygotic deposition of H3K27me3 in mouse embryosSemantic proximity Read ↗

Histone supply regulates S phase timing and cell cycle progression.Semantic proximity Read ↗

Histone variants--ancient wrap artists of the epigenome.Semantic proximity Read ↗

Histone variants and epigenetics.Semantic proximity Read ↗

The embryonic linker histone H1 variant of Drosophila, dBigH1, regulates zygotic genome activation.Semantic proximity Read ↗

Cell-cycle-dependent repression of histone gene transcription by histone H4Semantic proximity Read ↗

Histone Variants: The Nexus of Developmental Decisions and Epigenetic Memory.Semantic proximity Read ↗

Transgenerational Epigenetic Inheritance Factors Localize to Spatially and Temporally Ordered Liquid Droplet AssemblagesSemantic proximity Read ↗

Trailer Hitch tunes condensate phase behavior and mRNA partitioning to regulate P-body homeostasis during <i>Drosophila melanogaster</i> oogenesisSemantic proximity Read ↗

Gene regulation by the lysine demethylase KDM4A in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.