Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic complementation analysis showed distinct contributions of the N-terminal tail of H2A.Z to epigenetic regulations.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Feb 2016

Kusakabe Masayuki, Oku Hiroyuki, Matsuda Ryo, Hori Tetsuya, Muto Akihiko, Igarashi Kazuhiko, Fukagawa Tatsuo, Harata Masahiko

Abstract excerpt

H2A.Z is one of the most evolutionally conserved histone variants. In vertebrates, this histone variant has two isoforms, H2A.Z.1 and H2A.Z.2, each of which is coded by an individual gene. H2A.Z is involved in multiple epigenetic regulations, and in humans, it also has relevance to carcinogenesis. In this study, we used the H2A.Z DKO cells, in which both H2A.Z isoform genes could be inducibly knocked out, for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Cell Line

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Knockout Techniques

Share to Genetic Complementation Test

Share to Histones

Share to Mitosis

Share to Protein Isoforms

Source

Identifiers

PMID: 26833946
DOI: 10.1111/gtc.12327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic complementation analysis showed distinct contributions of the N-terminal tail of H2A.Z to epigenetic regulations.PMID 26833946Read ↗

Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progressionSemantic proximity Read ↗

Replacement of Arabidopsis H2A.Z with human H2A.Z orthologs reveals extensive functional conservation and limited importance of the N-terminal tail sequence for Arabidopsis developmentSemantic proximity Read ↗

Key functional regions in the histone variant H2A.Z C-terminal docking domain.Semantic proximity Read ↗

The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues.Semantic proximity Read ↗

What makes a histone variant a variant: Changing H2A to become H2A.Z.Semantic proximity Read ↗

H2A.Z functions to regulate progression through the cell cycle.Semantic proximity Read ↗

Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.Semantic proximity Read ↗

[H2A.Z: a histone variant that decorates gene promoters].Semantic proximity Read ↗

Sometimes one just isn't enough: do vertebrates contain an H2A.Z hyper-variant?Semantic proximity Read ↗

Random deposition of histone variants: A cellular mistake or a novel regulatory mechanism?Semantic proximity Read ↗

An improved functional analysis of linker-mediated complex (iFALC) strategy.Semantic proximity Read ↗

The nonessential H2A N-terminal tail can function as an essential charge patch on the H2A.Z variant N-terminal tail.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.