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Article

Evaluation of pleiotropic effects among common genetic loci identified for cardio-metabolic traits in a Korean population.

Cardiovascular diabetology - 1 Feb 2016

Kim Yun Kyoung, Hwang Mi Yeong, Kim Young Jin, Moon Sanghoon, Han Sohee, Kim Bong-Jo

Abstract excerpt

BACKGROUND: The genetic contribution to complex diseases or traits, including cardio-metabolic traits, has been elucidated recently by large-scale genome-wide association studies. These genome-wide association studies have indicated that most pleiotropic loci contain genes associated with lipids. Clinically, lipid related abnormalities are strongly associated with other diseases such as type 2 diabetes, coronary...

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Identifiers

PMID: 26833210
DOI: 10.1186/s12933-016-0337-1
PMCID: PMC4736473

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