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Article

SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents.

Obesity (Silver Spring, Md.) - 1 Feb 2012

Scherag André, Kleber Michaela, Boes Tanja, Kolbe Andreea-Liliana, Ruth Anne, Grallert Harald, Illig Thomas, Heid Iris M, Toschke André M, Grau Katrine, Sørensen Thorkild I A, Hebebrand Johannes, Hinney Anke, Reinehr Thomas

Abstract excerpt

Genome-wide association analyses (GWAS) contributed to the detection of a number of single-nucleotide polymorphisms (SNPs) associated with obesity. However, little is known about the impact of the obesity-risk alleles on weight loss-related phenotypes after lifestyle interventions. A recent meta-analysis of GWAS reported five genomic loci near or in the genes FTO, MC4R, TMEM18, SDCCAG8, TNKS/MSRA that were...

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Source

Identifiers

PMID: 22095114
DOI: 10.1038/oby.2011.339

Genes

SDCCAG8
FTO
MSRA
SDS
TMEM18
TNKS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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