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Towards a structural understanding of RNA synthesis by negative strand RNA viral polymerases

28 Jan 2016

Abstract excerpt

Negative strand RNA viruses (NSVs), which may have segmented (sNSV) or non-segmented genomes (nsNSV) are responsible for numerous serious human infections such as Influenza, Measles, Rabies, Ebola, Crimean Congo Haemorrhagic Fever and Lassa Fever. Their RNA-dependent RNA polymerases transcribe and replicate the nucleoprotein coated viral genome within the context of a ribonucleoprotein particle. We review the...

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Identifiers

PMID: 26826467
DOI: 10.1016/j.sbi.2016.01.002

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