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Structures and Mechanisms of Nonsegmented, Negative-Strand RNA Virus Polymerases

3 May 2023

Abstract excerpt

, have a genome consisting of a single strand of negative-sense RNA. Integral to the nsNSV replication cycle is the viral polymerase, which is responsible for transcribing the viral genome, to produce an array of capped and polyadenylated messenger RNAs, and replicating it to produce new genomes. To perform the different steps that are necessary for these processes, the nsNSV polymerases undergo a series of...

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PMID: 37137281
DOI: 10.1146/annurev-virology-111821-102603

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