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Influenza a virus antiparallel helical nucleocapsid-like pseudo-atomic structure

21 Nov 2024

Abstract excerpt

Influenza A viruses are responsible for human seasonal epidemics and severe animal pandemics with a risk of zoonotic transmission to humans. The viral segmented RNA genome is encapsidated by nucleoproteins (NP) and attached to the heterotrimeric polymerase, forming the viral ribonucleoproteins (vRNPs). Flexible helical vRNPs are central for viral transcription and replication. In this study, we present an...

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PMID: 39673795
DOI: 10.1093/nar/gkae1211

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