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Article

Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2016

Peeters Miriam C, Mos Iris, Lenselink Eelke B, Lucchesi Martina, IJzerman Adriaan P, Schwartz Thue W

Abstract excerpt

The adhesion G protein-coupled receptors [ADGRs/class B2 G protein-coupled receptors (GPCRs)] constitute an ancient family of GPCRs that have recently been demonstrated to play important roles in cellular and developmental processes. Here, we describe a first insight into the structure-function relationship of ADGRs using the family member ADGR subfamily G member 4 (ADGRG4)/GPR112 as a model receptor. In a...

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Identifiers

PMID: 26823453
DOI: 10.1096/fj.201500110

Genes

ADGRG4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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