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Article

Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans.

Genome biology - 29 Jan 2016

Kornienko Aleksandra E, Dotter Christoph P, Guenzl Philipp M, Gisslinger Heinz, Gisslinger Bettina, Cleary Ciara, Kralovics Robert, Pauler Florian M, Barlow Denise P

Abstract excerpt

BACKGROUND: Long non-coding RNAs (lncRNAs) are increasingly implicated as gene regulators and may ultimately be more numerous than protein-coding genes in the human genome. Despite large numbers of reported lncRNAs, reference annotations are likely incomplete due to their lower and tighter tissue-specific expression compared to mRNAs. An unexplored factor potentially confounding lncRNA identification is...

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Identifiers

PMID: 26821746
DOI: 10.1186/s13059-016-0873-8
PMCID: PMC4731934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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