Article

Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA–sequencing data

2017-11-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Protein-coding RNAs (mRNA) have been the primary target of most transcriptome studies in the past, but in recent years, attention has expanded to include long non-coding RNAs (lncRNA). lncRNAs are typically expressed at low levels, and are inherently highly variable. This is a fundamental challenge for differential expression (DE) analysis. In this study, the performance of...

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Literature Corpus work: f1021fc5-51a0-513a-a4a5-78970e12c2eb
DOI: 10.1101/220129

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