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Article

Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II).

Gerontology - 1 Jan 2016

Lill Christina M, Liu Tian, Norman Kristina, Meyer Antje, Steinhagen-Thiessen Elisabeth, Demuth Ilja, Bertram Lars

Abstract excerpt

BACKGROUND: Body mass index (BMI), bone mineral density (BMD), and telomere length are phenotypes that modulate the course of aging. Over 40% of their phenotypic variance is determined by genetics. Genome-wide association studies (GWAS) have recently uncovered >100 independent single-nucleotide polymorphisms (SNPs) showing genome-wide significant (p < 5 × 10-8) association with these traits. OBJECTIVE: To test...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26821332
DOI: 10.1159/000438900

Genes

AKAP11
FTO
MEPE
SMG6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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