Article
A stop-codon of the phosphodiesterase 11A gene is associated with elevated blood pressure and measures of obesity.
Journal of hypertension - 1 Mar 2016
Ohlsson Therese, Lindgren Arne, Engström Gunnar, Jern Christina, Melander Olle
Abstract excerpt
OBJECTIVE: To identify stop-codon variants associated with blood pressure (BP). METHODS: Illumina exome chip was genotyped in 5453 individuals of the population-based Malmö Diet and Cancer Study. We compared BP levels between carriers and noncarriers of all stop-codon variants found in at least 10 individuals and characterized these further based on literature evidence of functionality. Next, the association to...
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