Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels.

doi:10.1007/s00109-013-1062-9

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Article

Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2013

Breitfeld Jana, Heiker John T, Böttcher Yvonne, Schleinitz Dorit, Tönjes Anke, Weidle Kerstin, Krause Kerstin, Kuettner E Bartholomeus, Scholz Markus, Kiess Wieland, Sträter Norbert, Beck-Sickinger Annette G, Stumvoll Michael, Körner Antje, Blüher Matthias, Kovacs Peter

Abstract excerpt

UNLABELLED: A recent genome-wide association study suggests that genetic variation within the vaspin gene might contribute to the variability in circulating serum visceral adipose tissue-derived serine protease inhibitor (vaspin) concentrations. Here, we analyzed the functional consequences of the rare variant rs61757459 predicting a premature stop codon and its impact on circulating serum vaspin concentrations....

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PMID: 23756768
DOI: 10.1007/s00109-013-1062-9

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SERPINA12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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