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Article

Analysis of Low Frequency Protein Truncating Stop-Codon Variants and Fasting Concentration of Growth Hormone.

PloS one - 1 Jan 2015

Hallengren Erik, Almgren Peter, Engström Gunnar, Persson Margaretha, Melander Olle

Abstract excerpt

BACKGROUND: The genetic background of Growth Hormone (GH) secretion is not well understood. Mutations giving rise to a stop codon have a high likelihood of affecting protein function. OBJECTIVES: To analyze likely functional stop codon mutations that are associated with fasting plasma concentration of Growth Hormone. METHODS: We analyzed stop codon mutations in 5451 individuals in the Malmö Diet and Cancer study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26086970
DOI: 10.1371/journal.pone.0128348
PMCID: PMC4472854

Genes

MAF
ZNF77

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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