Clinical impact of small subclones harboring <i>NOTCH1</i> , <i>SF3B1</i> or <i>BIRC3</i> mutations in chronic lymphocytic leukemia

Abstract excerpt

Large-scale sequencing approaches have shown that chronic lymphocytic leukemia (CLL) is composed of a mosaic of leukemic subpopulations, each defined by distinct genetic lesions.[1][1]–[4][2] The application of ultra-deep-next generation sequencing (NGS) to track TP53 mutated subclones in CLL has

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced Breast Cancer Therapies
• Share to Cancer-related Molecular Pathways
• Share to Chronic Lymphocytic Leukemia Research