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Article

Next-generation sequencing in chronic lymphocytic leukemia.

Seminars in hematology - 1 Oct 2013

Villamor Neus, López-Guillermo Armando, López-Otín Carlos, Campo Elías

Abstract excerpt

The use of next-generation sequencing (NGS) has expanded our knowledge of the genomic alterations in chronic lymphocytic leukemia (CLL) and provides new tools for analyzing leukemic clonal architecture. Recent studies have demonstrated substantial differences in genomic alterations between mutated and unmutated IGHV subgroups, which reflect distinct molecular pathways and mutagenic mechanisms in the pathogenesis...

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Identifiers

PMID: 24246696
DOI: 10.1053/j.seminhematol.2013.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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