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Article

Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma.

Diagnostic pathology - 27 Jan 2016

Diamandis Phedias, Ferrer-Luna Ruben, Huang Raymond Y, Folkerth Rebecca D, Ligon Azra H, Wen Patrick Y, Beroukhim Rameen, Ligon Keith L, Ramkissoon Shakti H

Abstract excerpt

BACKGROUND: Molecular profiling has uncovered genetic subtypes of glioblastoma (GBM), including tumors with IDH1 mutations that confer increase survival and improved response to standard-of-care therapies. By mapping the genetic landscape of brain tumors in routine clinical practice, we enable rapid identification of targetable genetic alterations. CASE PRESENTATION: A 29-year-old male presented with new onset...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26817999
DOI: 10.1186/s13000-016-0455-9
PMCID: PMC4729030

Genes

STAT6
NAB2
IDH1
ATRX
GFAP
OLIG2
SOX2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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