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DNA-hypomethylation in the TNF-alpha gene predicts rheumatoid arthritis classification in patients with early inflammatory symptoms

2023-05-23

Abstract excerpt

Biomarkers for the classification of rheumatoid arthritis (RA), and particularly of anti-citrullinated peptide antibody (ACPA) negative patients, remains an important hurdle for the early initiation of treatment despite the use of 2010 classification criteria. Taking advantage of DNA-methylation patterns specific to early RA, quantitative methylation-specific qPCR (qMSP) offers a robust technology for the developm...

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Literature Corpus work
386377de-86a0-5690-bfd2-8b02d8d04aa0
DOI
10.21203/rs.3.rs-2952435/v1
Open publication

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DNA-hypomethylation in the TNF-alpha gene predicts rheumatoid arthritis classification in patients with early inflammatory symptomsDOI 10.21203/rs.3.rs-2952435/v1
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