Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.

Cancer letters - 1 Apr 2016

Liu Tang, Shen Jacson K, Li Zhihong, Choy Edwin, Hornicek Francis J, Duan Zhenfeng

Abstract excerpt

Sarcomas include some of the most aggressive tumors and typically respond poorly to chemotherapy. In recent years, specific gene fusion/mutations and gene over-expression/activation have been shown to drive sarcoma pathogenesis and development. These emerging genomic alterations may provide targets for novel therapeutic strategies and have the potential to transform sarcoma patient care. The RNA-guided nuclease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to CRISPR-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CRISPR-Cas Systems

Share to Gene Expression Regulation, Neoplastic

Share to Gene Targeting

Share to Genetic Association Studies

Share to Genetic Therapy

Share to Sarcoma

Source

Open in PubMed Open full text

Identifiers

PMID: 26806808
DOI: 10.1016/j.canlet.2016.01.030
PMCID: PMC4772675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.PMID 26806808Read ↗

Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.Semantic proximity Read ↗

CRISPR/Cas9-Mediated Genome Editing in Cancer TherapySemantic proximity Read ↗

Application of CRISPR/Cas9 Technology in Cancer Treatment: A Future Direction.Semantic proximity Read ↗

Current Status of CRISPR/Cas9 Application in Clinical Cancer Research: Opportunities and ChallengesSemantic proximity Read ↗

CRISPR/Cas9 technology in tumor research and drug development application progress and future prospectsSemantic proximity Read ↗

Engineering CRISPR/Cas9 therapeutics for cancer precision medicineSemantic proximity Read ↗

CRISPR-Cas9 in basic and translational aspects of cancer therapySemantic proximity Read ↗

Precision Oncology in the CRISPR Era: Applications and Future Horizons in Cancer TherapySemantic proximity Read ↗

Precision Oncology in the CRISPR Era: Applications and Future Horizons in Cancer TherapySemantic proximity Read ↗

Harnessing the evolving CRISPR/Cas9 for precision oncologySemantic proximity Read ↗

CRISPR-Cas9 systems: versatile cancer modelling platforms and promising therapeutic strategies.Semantic proximity Read ↗

CRISPR/Cas9 Genome Editing in Oncology: Mechanisms, Therapeutic Platforms and Translational ChallengesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.