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Current Status of CRISPR/Cas9 Application in Clinical Cancer Research: Opportunities and Challenges

14 Feb 2022

Abstract excerpt

Cancer is considered by not only multiple genetic but also epigenetic amendments that drive malignant cell propagation and consult chemo-resistance. The ability to correct or ablate such mutations holds enormous promise for battling cancer. Recently, because of its great efficiency and feasibility, the CRISPR-Cas9 advanced genome editing technique has been extensively considered for therapeutic investigations of...

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PMID: 35205694
DOI: 10.3390/cancers14040947

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