Article
Genetic variants of CDH13 determine the susceptibility to chronic obstructive pulmonary disease in a Chinese population.
Acta pharmacologica Sinica - 1 Mar 2016
Yuan Yi-ming, Zhang Jin-long, Xu Si-cheng, Ye Ren-song, Xu Dan, Zhang You, Zhang Yan-Jie, Chen Yu-long, Liu Yu-lan, Su Zhi-guang
Abstract excerpt
AIM: Adiponectin has been implicated in the development of chronic obstructive pulmonary disease (COPD). The CDH13 gene encodes T-cadherin that is an adiponectin receptor, and genetic variants of CDH13 determine blood adiponectin levels. The aim of this study was to investigate the effects of CDH13 variants on COPD susceptibility in a Chinese population. METHODS: Ten single-nucleotide polymorphisms (SNP) in CDH13...
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