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Article

Association between the interleukin-13 gene and development of chronic obstructive pulmonary disease in southern Chinese Han population: a case-control study.

Chinese medical journal - 1 Dec 2013

Gong Yi, Shi Guo-chao, Wan Huan-ying, Yang Kun, Pan Chun-ming, Cheng Qi-jian, Dai Ran-ran, Li Qing-yun, Li Min, Zhou Min, Guo Yi

Abstract excerpt

BACKGROUND: Interleukin-13 (IL-13) has been implicated to be responsible for recruitment of inflammatory cells from the blood to the lung, regulation of matrix metalloproteinase and induction of mucin production and secretion in chronic obstructive pulmonary disease (COPD). We determined plasma IL-13 levels in patients with COPD and investigated its association with common polymorphisms of IL-13 gene in a...

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PMID: 24286397

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