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Article

Genetic variation in CDH13 is associated with lower plasma adiponectin levels but greater adiponectin sensitivity in East Asian populations.

Diabetes - 1 Dec 2013

Gao He, Kim Yu-Mi, Chen Peng, Igase Michiya, Kawamoto Ryuichi, Kim Mi Kyung, Kohara Katsuhiko, Lee Jeannette, Miki Tetsuro, Ong Rick Twee-Hee, Onuma Hiroshi, Osawa Haruhiko, Sim Xueling, Teo Yik Ying, Tabara Yasuharu, Tai E Shyong, van Dam Rob M

Abstract excerpt

Variants in the CDH13 gene have been identified as determinants of blood levels of adiponectin, an insulin-sensitizing adipokine. However, their association with other metabolic risk factors remains unclear. We examined variants at CDH13 in relation to total and high-molecular-weight (HMW) adiponectin using data from a genome-wide association study performed in 2,434 Singaporean Chinese with replication in up to...

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Source

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Identifiers

PMID: 24009259
DOI: 10.2337/db13-0129
PMCID: PMC3837060

Genes

CDH13

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Genetic variation in CDH13 is associated with lower plasma adiponectin levels but greater adiponectin sensitivity in East Asian populations.PMID 24009259Read ↗

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