Article
CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.
Journal of atherosclerosis and thrombosis - 1 Jan 2016
Kitamoto Aya, Kitamoto Takuya, Nakamura Takahiro, Matsuo Tomoaki, Nakata Yoshio, Hyogo Hideyuki, Ochi Hidenori, Kamohara Seika, Miyatake Nobuyuki, Kotani Kazuaki, Mineo Ikuo, Wada Jun, Ogawa Yuji, Yoneda Masato, Nakajima Atsushi, Funahashi Tohru, Miyazaki Shigeru, Tokunaga Katsuto, Masuzaki Hiroaki, Ueno Takato, Chayama Kazuaki, Hamaguchi Kazuyuki, Yamada Kentaro, Hanafusa Toshiaki, Oikawa Shinichi, Sakata Toshiie, Tanaka Kiyoji, Matsuzawa Yuji, Hotta Kikuko
Abstract excerpt
AIM: Visceral fat accumulation contributes to the development of metabolic syndrome. As visceral fat accumulation increases, adiponectin levels decrease; therefore, adiponectin provides a link between visceral fat accumulation and metabolic disorders. Genome-wide association studies (GWASs) have identified genetic variations in the cadherin 13 (CDH13) gene that are associated with adiponectin levels. METHODS: We...
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