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Article

Structural and evolutionary insights into endogenous alpha-phospholipase A2 inhibitors of Latin American pit vipers.

Toxicon : official journal of the International Society on Toxinology - 15 Mar 2016

Estevão-Costa Maria Inácia, Fernandes Carlos Alexandre H, Mudadu Maurício de Alvarenga, Franco Glória Regina, Fontes Marcos Roberto M, Fortes-Dias Consuelo Latorre

Abstract excerpt

Phospholipases A2 are major components of snake venoms (svPLA2s) and are able to induce multiple local and systemic deleterious effects upon envenomation. Several snake species are provided with svPLA2 inhibitors (sbPLIs) in their circulating blood, which confer a natural resistance against the toxic components of homologous and heterologous venoms. The sbPLIs belong to any of three structural classes named α, β...

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PMID: 26806211
DOI: 10.1016/j.toxicon.2016.01.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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